178. Harnessing the Healing Power of Stem Cells with Dr. Jeff Gross.
Harnessing the Healing Power of Stem Cells with Dr. Jeff Gross.
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Email: elemental.evanhw@gmail.com
In this episode of the Elemental Evan Podcast, host Evan is joined by Dr. Jeffrey Gross, a trained neurological surgeon specializing in athletic injuries, spine procedures, and the founder of ReCelebrate, focusing on anti-aging and regenerative medicine through stem cells. Dr. Gross shares his in-depth knowledge on the role of stem cells in healing, regeneration, and anti-aging, explaining the source, functionality, and applications of stem cells and exosomes in medical treatment.
They discuss the potential of stem cells in treating various conditions, including joint degeneration, and kidney failure, emphasizing the importance of a holistic approach to health that includes diet, exercise, sleep, and the integration of regenerative medicine. Additionally, Dr. Gross highlights the cutting-edge research in regenerative biologics, specifically targeting cancer with exosomes and mitochondrial transfer therapy as future directions. The episode encourages listeners to consider regenerative methods as part of their health and wellness routine and provides information on how to contact Dr. Gross for those interested in exploring stem cell therapy.
03:43 Deep Dive into Stem Cells with Dr. Jeffrey Gross
06:03 Exploring the World of Regenerative Medicine
17:23 The Power of Exosomes in Regenerative Therapy
20:01 Lifestyle Choices and Their Impact on Stem Cell Activity
20:54 Future of Stem Cell Use in Treating Advanced Diseases
22:05 Exploring the Versatility of Exosomes in Medical Treatment
23:18 The Power of Fasting and Bone Broth for Gut Health
23:32 Harnessing Hormetic Activities for Stem Cell Benefits
26:43 The Role of Diet and Supplements in Stem Cell Maintenance
29:18 Innovations in Regenerative Medicine and Longevity
34:23 A Deep Dive into Zombie Cells and Mitochondrial Health
37:30 Future Directions in Regenerative Medicine and Contact Information
Transcript
Hey, what's going on, everyone.
2
:Welcome to the elemental Ivan
podcast on this podcast, I break
3
:down health topics from a holistic
and simplified perspective.
4
:That way you can walk away from all
of these episodes, with some tools in
5
:your belt, and some know how on how to
change your health for the better and
6
:take control of your own health as well.
7
:On today's episode, we're
going to be joined by a guest.
8
:And it's always a pleasure for
me to have somebody on the show.
9
:It's truly just a learning opportunity
for myself as well as for all of you.
10
:And today we're joined by Dr.
11
:Jeffrey Gross.
12
:He's the founder of reseller.
13
:Great.
14
:Which is focusing on anti-aging
and regenerative medicine.
15
:Uh, this Dr.
16
:Jeffrey Gross is incredibly knowledgeable
on all things, stem cells, and that's
17
:really what we dive into today.
18
:He's a trained neurological surgeon
and specializes specifically in
19
:athletic injuries and spine procedures.
20
:And he's really focusing on longevity
and just helping us to age slower and
21
:feel better as we continue to age.
22
:And personally, for me, I think stem
cells are a really interesting, um,
23
:practice and something that we're going
to see a lot more of in the future.
24
:I think we're really just kind of on the.
25
:The edge of it at the moment,
like we're about to really jump
26
:over into a new, uh, kind of.
27
:Whole field of science and,
um, healing for the body.
28
:Uh, with the use of stem cells.
29
:So really excited to have him on today.
30
:And if you'd like to get in touch with
him, of course, we're going to have all
31
:of his information in the description
or the show notes of the show today.
32
:Uh, so feel free to check that
out and get in touch with him.
33
:See what he's all about.
34
:Uh, down there.
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:We're also going to have, of
course, all of our awesome, uh,
36
:sponsors and partners of the show.
37
:And go ahead and please check out
some of the links there because we
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:have some really incredible stuff.
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:Uh, one of my favorites of course,
is always going to be the energy
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:bit spirulina and chlorella.
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:One of my favorite things
to take every single day.
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:, if you haven't already listened to this
show, many times, , then this is probably
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:your first time hearing about it, but the
spirulina and chlorella over at energy
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:bits is truly the best of the best.
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:It's my favorite spirulina.
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:Uh, and chlorella products
out there, super high quality.
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:And for me personally, I feel
the difference when I take them.
48
:And it's also just a great way
to make sure you're covering your
49
:bases on getting in those vitamins
and minerals every single day.
50
:And of course the higher levels
of chlorophyll never hurt.
51
:Uh, They are always super good.
52
:Um, I've actually been eating a.
53
:Very high amount of seafood lately.
54
:Uh, the last couple of weeks.
55
:And therefore I have also increased
my spirulina and specifically
56
:my chlorella intake because of
the high levels of chlorophyll.
57
:And because they are able to, uh,
chlorophyll is able to help get
58
:heavy metals out of your blood.
59
:Uh, which obviously for eating seafood,
that's going to be a good idea to do that.
60
:So go ahead and check that out as well.
61
:Of course, you're gonna get that 20%
off for being a listener to the show.
62
:And, uh, yeah, without further ado,
let's get into today's episode with Dr.
63
:Jeff.
64
:He's a really awesome guy and I was
super happy to have him on the show.
65
:I know you all are going to have
a ton to take away from today's
66
:episode, so I hope you all enjoy.
67
:And, uh, without any further
ado, let's get to it.
68
:Peace.
69
:evan-_2_05-01-2024_165309: Welcome
to the elemental Evan podcast today.
70
:We're joined with the one and only.
71
:Dr.
72
:Jeff, he is a very awesome and
patient person while I work here
73
:with my technical difficulties.
74
:So you're already a great person in
my books, but welcome to the show.
75
:dr--jeff-gross_2_05-01-2024_165332:
Thanks so much.
76
:And thanks for having me on.
77
:This is great.
78
:evan-_2_05-01-2024_165309: Yeah.
79
:So I know we already covered this question
and it got erased, but, uh, I wanted to
80
:start with, uh, the very base here, which
is simply, you know, what are stem cells
81
:and what are their functions in the body
82
:dr--jeff-gross_2_05-01-2024_165332:
Basically stem cells are the very
83
:cells that made us in the first place.
84
:When we are an embryo inside of
our mothers, the cells that are
85
:creating us and developing our
organs and our limbs and everything
86
:are very powerful stem cells.
87
:And then later when we're born and
even become an adult, stop growing, you
88
:know, we, we maintain sort of useful,
but not fully powerful stem cells.
89
:Uh, we don't have the stem cells in their
current form that can make a new person,
90
:but they can help renew a lot of our
cells that get used up or, you know, Um,
91
:you know, age, the most common examples
of cells that renew are like skin cells.
92
:They, you know, they renew all the time.
93
:Uh, we, we make new, you know,
cells that make hair and make nails,
94
:even our liver and other organ.
95
:Uh, those cells can renew themselves.
96
:Stem cells are also harbored in our
body to help us fight inflammation, uh,
97
:help our immune system, help us heal.
98
:So for example, if I
cut or something, they.
99
:They bring in all the healing factors
and other cells to help us repair.
100
:So they, they are about restoration,
regeneration, and repair.
101
:evan-_2_05-01-2024_165309: gotcha.
102
:And so.
103
:As we get older, we obviously produce
less stem cells as time goes on.
104
:Correct.
105
:dr--jeff-gross_2_05-01-2024_165332:
Well, we, we probably have, you know, a
106
:diminishing supply of them, but like all
our cells that are exposed to the modern
107
:world, uh, things in our water, in our
food, in our air, electromagnetic fields.
108
:All kinds of things.
109
:All of our cells get, you know, kind
of gunked up, they get inflamed,
110
:uh, they have changes within them.
111
:Some of them are so bad they become what
are called senescent or zombie cells.
112
:So, that can happen to our stem
cells too, and when our stem cells
113
:basically become less efficient at
doing what they're supposed to do.
114
:And that's why regenerative medicine
is now a thing and we could, we could
115
:use that knowledge to help, you know,
our older cells and our older bodies
116
:act and repair like a younger person.
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:evan-_2_05-01-2024_165309: Gotcha.
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:You, you mentioned regenerative repair.
119
:What, what exactly is that?
120
:dr--jeff-gross_2_05-01-2024_165332: So
the whole, the whole idea of regeneration
121
:is to replace a cell that's no good,
no longer useful, senescent, you know,
122
:just, you know, what stem cells do,
they are regenerative in their nature.
123
:Other things are regenerative, like growth
factors, growth factors you might find in
124
:what's called PRP or platelet rich plasma.
125
:There are regenerative, um, you know,
phytonutrients in plants and in fruits.
126
:And, and, you know, even protein
has some regenerative capabilities.
127
:There are even some medications and even
some lifestyle epigenetic activities.
128
:You know, things like, uh, proper
exercise using your muscles.
129
:Uh, stretching, yoga, breathing
techniques, meditation, uh, these
130
:are called lifestyle or epigenetic
factors and they do stimulate stem
131
:cell activity because they are
regenerative in their own nature.
132
:evan-_2_05-01-2024_165309: Wow.
133
:Okay.
134
:That's super interesting.
135
:So there, there are certain practices
that we can be doing right now.
136
:Essentially the things that keep us
the most healthy already that we know,
137
:you know, things like exercise and
breath, like you were mentioning, and
138
:so by doing those practices, they are.
139
:Essentially inducing the, the action
of, of our stem cells, correct?
140
:dr--jeff-gross_2_05-01-2024_165332: Right.
141
:And in fact, there are, there's some
great studies, uh, you can Google, you
142
:know, yoga and stem cells and there, there
are actually studies showing increase
143
:in circulating stem cells and activity.
144
:And people with a regular yoga practice,
145
:evan-_2_05-01-2024_165309: Wow.
146
:So that's why all the
yogis look so young, huh?
147
:dr--jeff-gross_2_05-01-2024_165332: right?
148
:evan-_2_05-01-2024_165309: Very cool.
149
:Um, and so in terms of stem cells,
well, actually, I think, would you
150
:walk us through what, uh, what, um,
Basically, the practice of using stem
151
:cells for therapy would look like,
is it, you know, do we pull these
152
:from our own body, from someone else?
153
:Do we get them from, you know, I,
I believe, is it what, from the
154
:spinal or from the spine or even
from fat cells if I'm not mistaken?
155
:Um, yeah.
156
:How, how does that all work?
157
:dr--jeff-gross_2_05-01-2024_165332: Yeah,
let's, uh, let's do a little stem cell
158
:one on one, uh, because you're right.
159
:There's a lot of misinformation,
disinformation and, and let's,
160
:let's set the record straight.
161
:So, you know, stem cells, we've,
we've been unknowingly tapping
162
:into this for a long time.
163
:And, you know, I, I, most of
my medical practice for many
164
:years was as a spine surgeon.
165
:And so.
166
:We would always use some bone
marrow and doing a bone fusion,
167
:for example, because we want that
those rich healing immune cells.
168
:So what we were really doing, though,
is tapping into stem cell activity.
169
:Um, stem cells for therapeutic purposes
can be harvested from your own body.
170
:Uh, they can be taken from fat,
although that's not always the best.
171
:They are useful, um, because too
much fat, like an obese person, Can
172
:be giving off and pro inflammatory
signal that we don't want.
173
:Bone marrow is probably the
most robust source of our
174
:healthy stem cell population.
175
:And if you think about it, the more
stem cells you have, the more The
176
:healthier you are, the fewer diseases
you have and the longer you will live.
177
:And to correlate with that, as,
uh, as you lose bone density,
178
:bone mass, you're losing your
bone marrow and your stem cells.
179
:So, uh, many, many people know
that a lack of bone density.
180
:is correlated with a lack
of longevity and vice versa.
181
:So what you're really doing, you
support your bones by using your muscles
182
:and you support your bone marrow.
183
:You're supporting your stem cells.
184
:You'll live longer.
185
:Stem cells can also be harvested from
donors and those donors are usually
186
:mothers who just gave birth to a baby by
C section and instead of throwing away The
187
:placenta, the umbilical cord, the amniotic
fluid, it can be donated and tested and
188
:screened by reputable suppliers and labs
and, and used for regenerative purposes.
189
:And when you compare, you know, my 58
year old stem cells to fresh out of
190
:the womb, unadulterated stem cells that
have not been exposed to the world's
191
:pro inflammatory oxidative problems.
192
:I like the younger stuff.
193
:evan-_2_05-01-2024_165309: Yeah.
194
:No, but does getting stem cells from.
195
:Someone else are they less effective
as opposed to using your own stem
196
:cells that might be I don't know
like more Accustomed to your body
197
:like does that play a role at all?
198
:dr--jeff-gross_2_05-01-2024_165332:
No, you know, stem cells and stem
199
:cell related, uh, signaling particles
called exosomes, um, uh, which are
200
:part of the family of regenerative
biologics are not known to have
201
:any meaningful immune response.
202
:So they're not likely to be rejected.
203
:They don't harbor The molecules
on the cell surface to make them
204
:look like an individual, the kind
of things you would look for.
205
:If you're looking for a bone donor
matched, you know, you know, for
206
:a recipient, it's not like that.
207
:They're very neutral that
we call immunoprivileged.
208
:evan-_2_05-01-2024_165309: Hmm.
209
:dr--jeff-gross_2_05-01-2024_165332:
get to enter the body without.
210
:causing any stir.
211
:evan-_2_05-01-2024_165309: Gotcha.
212
:Okay Now I have a kind of a weird question
here, but You know, I know it's a kind of
213
:a becoming a more common practice in at
least like the Western world where after
214
:giving birth Some mothers will encapsulate
their their you know, their placenta
215
:and consume it now are there benefits?
216
:With stem cells through consuming
it that way, or does it have to
217
:go through a different process?
218
:dr--jeff-gross_2_05-01-2024_165332:
So there are benefits from
219
:consuming the placenta.
220
:These are well known health
benefits in many cultures.
221
:Uh, the West is a little
late to the to the game.
222
:But, um, you know, in other
cultures, they just eat it.
223
:They just cook it up and eat it, right?
224
:So the placenta is rich in stem
cell and stem cell derived Signaling
225
:factors called exosomes, as I
mentioned, and those exosomes do
226
:a lot of the work of encouraging
ourselves to behave in a more anti
227
:inflammatory way and anti inflammatory
is usually works against disease.
228
:So that's good.
229
:We want that.
230
:And, um, anti inflammatory is anti aging.
231
:So, um, we see this also
in other, uh, examples.
232
:For example, bone broth.
233
:Uh, because it's from bone marrow or
bones, it has, it's rich in exosomes
234
:and stem cell derived exosomes, cell
signaling from exosomes to encourage
235
:our own cells to behave better.
236
:Uh, we see this, if you, if
you go to a fancy restaurant,
237
:they might serve bone marrow.
238
:Uh, and what is your mother and your
grandmother make you when you're sick?
239
:They make you chicken soup from the
chicken stock, which is from the exosomes
240
:and the stem cells and the chicken bones.
241
:So this is not new.
242
:Plants also make exosomes.
243
:I know, uh, on your show before you've
spoken about chlorophyll and other things.
244
:I mean, these are the plant derived
exosomes stimulate our stem cells as well.
245
:Yeah,
246
:evan-_2_05-01-2024_165309: like I
only typically hear of the correlation
247
:between stem cells and I would say I
guess like animal products or Uh, even
248
:I guess human animals really as well.
249
:But I mean, um, yeah, I've never
heard of that with uh with plants
250
:as well So that's super interesting
251
:dr--jeff-gross_2_05-01-2024_165332:
it's it's very big now a lot of you
252
:know, these You know, we'll call them,
you know, fruits and vegetable powders.
253
:Supplements have been around
for a long time, getting
254
:better and better all the time.
255
:Um, They, they are rich in
exosomes from plant cells.
256
:Those exosomes carry a similar cargo.
257
:The cargo is usually a growth
factors in small, well preserved
258
:proteins like heat shock protein.
259
:And I don't know if you've had
anyone on your show before has
260
:spoken about the health and longevity
benefits of sauna, uh, sauna use.
261
:It's because you get in this hot, uh, you
know, temperature and your cells release
262
:these proteins called heat shock proteins.
263
:They, they tend to be survival
proteins and they fight inflammation.
264
:They support longevity.
265
:And it turns out those same proteins
are found in these plant derived and
266
:stem cell derived exosomes from, from
the plants in the first group and from.
267
:Humans and other animals in the
second group that that's how much
268
:the similarities are between plants
and animals down when you get to
269
:the very primitive growth factors.
270
:evan-_2_05-01-2024_165309: Wow.
271
:That's wild.
272
:Yeah.
273
:It's, you know, actually I've spoken
about sauna before on the show, but
274
:I haven't really had someone speak
too much towards like heat shock
275
:proteins, like you just mentioned.
276
:And, uh, the real health benefits.
277
:I just know that the power of a sauna
is like even just using it once a week
278
:for not even a super long period of time
can have some massive health benefits.
279
:Um, but yeah, I haven't really
gone too deep on that one.
280
:Um, do you, do you have a
sauna that you use personally?
281
:dr--jeff-gross_2_05-01-2024_165332:
I'm just in the process of shopping
282
:for a new one, but I've been reading
more about it and doing a deep dive
283
:on different forms of hormesis, like,
you know, we want to build a little
284
:resilience in your body and make it
survive better with exercise, sauna.
285
:cold plunge, fasting.
286
:Those are, those are the big ones.
287
:evan-_2_05-01-2024_165309: Gotcha.
288
:Okay.
289
:So coming back to with stem cells being
used on different parts of the body.
290
:What, what do you typically
use stem cells for?
291
:I know you mentioned like
anti aging properties.
292
:You also, uh, I believe you've
mentioned before that, um, you know,
293
:can help with things like even was it
sciatica pain and Uh, as well, or like
294
:back pain and just injuries overall.
295
:Is that typically what you
would use stem cells for
296
:dr--jeff-gross_2_05-01-2024_165332:
Well, I would say we use them for a
297
:few different general groups of things.
298
:The low hanging fruit in my
practice is, is joint degeneration.
299
:Things that a doctor may call arthritis
or osteoarthritis or bone on bone or
300
:chondromalacia, which means wearing
down of the cartilage surfaces.
301
:Most of our patients come in with
joint pain, uh, inflammation.
302
:and they're trying to avoid
a joint replacement surgery.
303
:So we follow protocols that have
been around for 20 years in Europe.
304
:We're just late to the party.
305
:And, uh, we do specialized MRIs.
306
:We target the areas
that need the love most.
307
:And, um, the, the areas where, where we
get the benefit is actually in the bone
308
:marrow and what's called the subchondral
bone, just adjacent to the joint.
309
:So we're not injecting the joint.
310
:The cartilage, because the cartilage is
like hair, it's made from the bone, just
311
:like our scalp follicles make hair, the
bone makes the cartilage, the bone, the,
312
:the chondrocyte cells in the, in the bone.
313
:So we re stimulate the, the stem cells
and the chondrocytes and your own
314
:cells in the bone by injecting the
signaling factors that we call exosomes.
315
:Uh, we could do both stem cells too, but
exosomes I find are easier to handle.
316
:We can get a more concentrated dose.
317
:Uh, they travel further in the
tissue and last longer, and
318
:they're about half the price.
319
:evan-_2_05-01-2024_165309: now?
320
:Sorry.
321
:And the difference between stem cells and
exosomes, uh, what, what is it exactly?
322
:And then also do, do you derive
them from the exact same place?
323
:Like, do you pull them both from arrow?
324
:dr--jeff-gross_2_05-01-2024_165332: Yeah.
325
:So I, I'm only now using, uh, donated,
uh, perinatal products from someone who
326
:just had a baby and the exosomes are the
small, not that cells aren't small, but
327
:even smaller signaling factors, a little
bit of a membrane with these heat shock
328
:proteins, growth factors, micro RNAs.
329
:That the stem cell makes and, and if, if
you, if I were to give you, Evan, if I
330
:were to give you a stem cell injection
somewhere, those stem cells are making
331
:and delivering exosomes to you in, in
most, mostly the stem cells delivery
332
:factor, the exosomes are doing the work.
333
:So we're cutting out the middleman.
334
:So even though the whole buzzword here
is stem cell medicine, it's really
335
:the exosomes that are doing the work.
336
:We're just skipping right
to the medicine part.
337
:So we, we, we inject the exosomes
from the perinatal source.
338
:We don't have to harvest anything.
339
:And, uh, we have been demonstrating
in many patients, improvement in
340
:pain, improvement in function,
no longer needing a surgery.
341
:And, uh, we have some people we've
done MRIs before and after, separated
342
:by eight, nine months or longer.
343
:We've seen an increase in the thickness
of the cartilage in the knee, for
344
:example, after these injections.
345
:So, so we know we're stimulating
those bone cells to make
346
:those cartilage proteins.
347
:The cartilage itself in the joint
injection doesn't do as much because the
348
:cartilage is really biological rubber.
349
:It's not a lot of cells in there.
350
:There are some, but not a lot.
351
:evan-_2_05-01-2024_165309: Wow.
352
:Okay.
353
:I had no idea.
354
:So X exosomes is the thing we want to
really focus on here and, and utilize.
355
:Um, I know I've had, uh, A family friend,
I think he had something wrong with his
356
:rotator cuff and, uh, was using, uh, you
know, some stem cell therapy and, and
357
:he's received a lot of benefit from it.
358
:So definitely seems to be
something to this for sure.
359
:And super fascinating about cartilage.
360
:I actually did not know that.
361
:And that's a great.
362
:Uh, a way to think of it as like hair
growing out of, you know, your head,
363
:basically, like, that's super fascinating.
364
:dr--jeff-gross_2_05-01-2024_165332:
Yeah, the activity is in the bone and
365
:that's why people with inflammatory and
metabolic problems have osteoarthritis
366
:problems at a more accelerated rate.
367
:Because the status of their
body's cell activity is affecting
368
:the cells in their bone.
369
:And that's why they have more
problems with like knee pain and
370
:joint pain and things like that.
371
:evan-_2_05-01-2024_165309: Yeah.
372
:And I wonder too, if specifically doing
like resistance training would be most
373
:beneficial for, you know, stem cell
production or activity in the body
374
:due to, uh, kind of like the stress
that's being put on the bone and really
375
:causing it to, you know, adapt to
the stress that's being placed on it.
376
:And, uh, hopefully helping to.
377
:You know, stay away from things
like osteoporosis, but I wonder if
378
:that's kind of like, do you know
if that's one of the best methods
379
:in terms of Trying to increase that
380
:dr--jeff-gross_2_05-01-2024_165332:
it's some type of weight bearing
381
:resistance exercise is probably the
single easiest and best thing you can do
382
:for longevity because it's stimulating
maintenance of the bone marrow and thereby
383
:maintenance of the stem cell population.
384
:evan-_2_05-01-2024_165309: wow, that
is that's absolutely fascinating.
385
:So, um, okay.
386
:And now in terms of, uh, do we see like
stem cells being used for even possibly
387
:like, I don't know, like advanced
diseases down the road, like even.
388
:You know, I, I don't know, but any
kind of disease, like whether we're
389
:talking like from dementia to cancer
to any, any, you know, liver failure,
390
:do we see it being used for those?
391
:dr--jeff-gross_2_05-01-2024_165332:
Yeah, so let me cover that, but it's
392
:fair to say that, you know, I want all
your listeners to know that, you know,
393
:what everything I'm saying here is,
uh, with the knowledge that the FDA has
394
:not yet approved for marketing claims.
395
:anything involving stem cells or
biologics for treatment or cure.
396
:So what I'm telling you here are
things that we know from the scientific
397
:literature, things we've seen in our
office on, you know, observations,
398
:but we're not allowed to make
any claims, not like doctors make
399
:guarantees anyway, we really can't,
but I want to be clear about that.
400
:But having said that, yes,
I've used IV exosomes for, uh,
401
:stem cell derived exosomes.
402
:for people with failing kidneys,
uh, and kept them from dialysis.
403
:I don't know that I can do it for
everyone, but we've, we've done it.
404
:Uh, I've, I've helped people recovering
from heart attack and stroke.
405
:The earlier we get to them, the
better same with brain injury.
406
:Um, I don't have a big experience in
liver failure, but again, the organs.
407
:In the body, uh, do receive
a lot of blood flow.
408
:They do get the exosomes delivered
to them when we give them.
409
:Um, so it's possible we have people
we've done the breathing treatment with
410
:exosomes who have had like long COVID
syndromes and, and a different type of
411
:fibrotic or inflammatory lung problems.
412
:As long as there is an
inflammatory component.
413
:The exosomes are known to suppress
cellular inflammation activity generally.
414
:So people with autoimmune problems, uh,
you know, irritable bowel syndromes,
415
:and even some weird infections like
the long COVID or Lyme's disease, have
416
:some benefit in the inflammatory sense.
417
:evan-_2_05-01-2024_165309: Uh, so wild.
418
:Yeah.
419
:That's when you mentioned irritable bowel
syndrome, that's, that's me for sure.
420
:Um, I've gotten so much
better as time has gone on.
421
:Um, but still, you know, like still
navigating my way, uh, through trying to
422
:just get my gut totally where I want it.
423
:Uh, but I will say, One of the
big things has definitely been,
424
:um, fasting and bone broth.
425
:That's been a huge
combo that I really use.
426
:And, um, does fasting have any, uh,
benefits as well for STEM cells?
427
:dr--jeff-gross_2_05-01-2024_165332:
yeah, it's, it's one of the big
428
:hormetic activities that, uh,
fasting exercise, heat and cold.
429
:Those are probably the four big
ones, uh, you know, that build that
430
:resilience and, and stimulate the
release of survival proteins in the
431
:body that those proteins stimulate the,
you know, reset of the immune system.
432
:They stimulate the bone marrow
production of, um, stem cells and
433
:stem cell, you know, proliferation.
434
:And they stimulate, you know,
hormone release and things like that.
435
:So, yeah, that's, that's big.
436
:evan-_2_05-01-2024_165309: Awesome.
437
:Yeah, no, happy to hear that.
438
:I mean, I feel, I feel like there's,
There can be a limit with, uh, with
439
:fasting, you know, and it needs to be
done properly, but, um, it's always nice
440
:to just have some reassurance that, you
know, you're doing some good stuff with
441
:the fasting, but I've noticed a massive
benefit with, uh, with my gut health
442
:every time I've done a fast, especially,
uh, the longer fast, like going two or
443
:three days, uh, typically with fasting
and then especially following it up
444
:with the first meal of bone broth.
445
:It just seems to, for like a
week, my digestion is just.
446
:Top tier.
447
:Um, yeah, it's been, it's
been really massive for me.
448
:So I've been trying to work on things
like that, but it's interesting to
449
:hear that, you know, possibly using,
uh, stem cells for like even gut
450
:health can be really beneficial.
451
:It makes a lot of sense too.
452
:dr--jeff-gross_2_05-01-2024_165332: Yeah.
453
:It really, they really do
suppress body inflammation.
454
:We see this, we do some, um, uh,
inflammatory markers and biological age
455
:tests, you know, before a treatment and
then maybe a month or two after treatment.
456
:And we can see beneficial differences
in, in the whole body inflammation.
457
:And, and, and we know that
particularly with an immune problem.
458
:The suppressing inflammation
goes a long way.
459
:evan-_2_05-01-2024_165309: Wow.
460
:And what, what do you guys use
to track the biological age?
461
:dr--jeff-gross_2_05-01-2024_165332:
So, uh, there are a couple
462
:of different ways to do it.
463
:Uh, different tests on the market.
464
:One of my favorite ones is called
glycinate, which measures, uh, how
465
:many sugar molecules get appended
to your antibodies in your body.
466
:Uh, and we know with regular
aging that happens and we know the
467
:patterns and the profiles, cause
there's, there's specificity to it.
468
:And you can reverse that by changing
lifestyle, by changing what you take or
469
:receive, or you know, how you do things.
470
:So it's a way to measure biological age.
471
:Most of the tests on the market measure
intracellular things, or even, because
472
:antibodies are outside the cell.
473
:But inside the cell you've got You
know, um, telomeres at the end of
474
:your DNA and how long they are.
475
:You've got, uh, different,
different changes to the DNA.
476
:Uh, you know, it becomes, you know,
glycosylated over time, things like that.
477
:So that's, those are some
of the intracellular markers
478
:and those are good tests too.
479
:evan-_2_05-01-2024_165309: Okay.
480
:Gotcha.
481
:Um, yeah.
482
:And then you had mentioned.
483
:Multiple times already on the podcast,
but what, uh, what would be some of the
484
:big movers for just naturally taking
care of your, of your stem cells?
485
:Like, what are some of the things that
you do or would recommend for people
486
:in terms of, I know we mentioned like
yoga or resistance training and, um,
487
:you know, fasting and all that, but what
would be some of your, your really big
488
:movers you would focus on personally?
489
:dr--jeff-gross_2_05-01-2024_165332: Yeah.
490
:I mean, I would, I would make
sure there's exercises, part of
491
:your lifestyle that includes,
uh, resistance or weight bearing.
492
:Uh, I would include, uh, a real effort.
493
:To sleep restoratively, uh, by, you know,
the right amount of time, not too little,
494
:not too much, but you know, cold room,
dark room, no screens for an hour before.
495
:You know, mindfulness,
meditation, whatever it takes
496
:to really get some deep sleep.
497
:Most of us, uh, uh, you know, I'm a
big proponent of melatonin at bedtime.
498
:Even if you go to sleep fine,
you're not using it for that.
499
:You're using it to stimulate
the cell repair process during
500
:the dark cycle, which is night.
501
:So it's like the opposite of cortisol.
502
:And you need that hormone because we
really stopped making it after puberty.
503
:Um, uh, besides that, I think proper
diet, enough protein, clean diet, uh,
504
:stay away from the vegetable oils.
505
:Um, Uh, I, I am a carnivore,
uh, but I know there are a
506
:lot of people who are not.
507
:So those, those who are not really
need to work on getting quality
508
:protein and all the missing and branch
chains, uh, essential amino acids.
509
:I'm a big, big fan of omega 3.
510
:I think the vast majority of
Americans are underdosing themselves
511
:on fish oil or omega 3 supplements.
512
:If you look at the blue zones, they
have high omega 3 indexes, meaning
513
:Getting a lot more seafood, uh, and
omega 3s in their diet normally.
514
:And we need to work hard to do that.
515
:Um, and there's, there's, there's
really good literature to support that.
516
:Um, other, other nutritional gaps.
517
:I'm a big fan of vitamin
D3 supplementation.
518
:The sun does not make vitamin D3.
519
:It converts some vitamin D2 to vitamin D3.
520
:But you don't know how
much vitamin D2 you have.
521
:So you can't just go
out in the sun too much.
522
:You'll hurt your skin too.
523
:Uh, you really need to take a significant
amount of vitamin D3, so 5, 000 and
524
:even 10, 000 international units a
day, which you, you know, a multi, a
525
:multivitamin, a one a day might have
500 or a thousand, it's not enough.
526
:And we know that vitamin D3
reduces all cause mortality.
527
:And it really, if it's not, if
it's reducing all the things that
528
:kill you, you'll live longer.
529
:It's a longevity, uh, and anti
inflammatory, um, supplement.
530
:And there are many others.
531
:We could talk supplements for hours.
532
:Uh, so diet supplements, sleep,
exercise, um, and then, you
533
:know, you want to get fancy.
534
:We've talked about regenerative medicine.
535
:Do you, you know, if you can,
we, we can do IV exosomes.
536
:You can do stem cells.
537
:You don't have to leave
the country to do it.
538
:Um, the, the outfits outside the
country can advertise because they
539
:don't have the FDA to deal with.
540
:So you hear all kinds of claims, but
do your homework before you do that.
541
:Um, and there are even some, I'm
not a big pharmaceutical guy.
542
:I don't love that, but there are
some medications that are naturally
543
:found that are known to be longevity
medications like rapamycin people
544
:use now metformin or semi glutide,
particularly if your weight is high.
545
:to reduce sugar exposure.
546
:If you have insulin sensitivity problems,
that might be something for you.
547
:Um, there are even people using Cialis,
Viagra, and there are some of the
548
:statins, even though statins can cause
problems, some of them have now been
549
:found to be associated with longevity.
550
:So look it up.
551
:Longevity meds, And you'll
be surprised what you see.
552
:evan-_2_05-01-2024_165309:
Oh, that's awesome.
553
:And no, I'm thank you for mentioning that.
554
:I really, uh, I appreciate.
555
:You know, you taking a kind of a holistic
approach to really looking at every
556
:aspect of life and, and recognizing that,
like, you know, if you have the time and
557
:you're able and which we all should be
doing, like, let's try these methods.
558
:But, you know, when it gets to a
point where you're bone on bone or,
559
:you know, really you need the extra
help, um, you know, come in and, and,
560
:and like you said, do the research,
find a good practitioner like yourself
561
:and, uh, and come get checked out.
562
:And now you had mentioned you were a.
563
:Sorry.
564
:You, you, what was your
profession prior to this?
565
:Had you
566
:dr--jeff-gross_2_05-01-2024_165332:
Yeah, well, I still am a
567
:neurosurgeon with Spine Fellowship.
568
:So I treated neck and back pain
the vast majority of my career.
569
:And I went into regenerative
medicine just because a lot of
570
:my patients were like, Hey, doc,
we're trying not to have surgery.
571
:I'm like, yeah, I get it.
572
:I don't want you to have it either.
573
:But nothing else worked.
574
:How about stem cells, doc, you know?
575
:And you hear it enough times,
you know, like, okay, I'll, I'll
576
:start getting trained there.
577
:There, there's gotta be something there.
578
:So I started going back and getting
reeducated and about five, six years
579
:ago, this, this just blossomed and
I'm doing so much of, of regenerative
580
:medicine now compared to my old stuff.
581
:evan-_2_05-01-2024_165309: Wow.
582
:And so do you see like typical, uh,
surgeries that you would have had
583
:to have performed or, or, you know,
still do perform, but that you can now
584
:treat with just your, uh, with, with
using, um, these exosomes and stuff.
585
:dr--jeff-gross_2_05-01-2024_165332:
Well, we, we are trying these things
586
:to help people heal and avoid surgery.
587
:That's that's what we're doing.
588
:And we want to maintain our compliance
with the FDA by saying it that way.
589
:Uh, you know, but, uh, yeah, we're,
we're, we're seeing some, some
590
:benefits in many cases, and I'm
happy to offer it as an additional
591
:tool to delay or put off surgery.
592
:evan-_2_05-01-2024_165309: Gotcha.
593
:Yeah.
594
:And, and I really, uh, I
appreciate you mentioning that too.
595
:Cause yeah, it's, uh, usually
I hear of stem cell work being
596
:done like abroad pretty much.
597
:And so thank you for mentioning that.
598
:Um, yeah, like we have great practitioners
here and as well, like you said, you can't
599
:make these claims because of the FDA and,
and, you know, with, with reason, right.
600
:Um, but no, for, thank
you for mentioning that.
601
:And also on that note,
where are you based out of?
602
:dr--jeff-gross_2_05-01-2024_165332:
So my, my main practice here is in,
603
:uh, the suburb of Las Vegas, Nevada
called Henderson and near the airport.
604
:evan-_2_05-01-2024_165309: Very nice.
605
:Nice.
606
:Um, yeah.
607
:And so like typically, so if someone
wanted to like get in touch with you, what
608
:would be some of the major things that you
would be feel comfortable working with?
609
:Like you mentioned
cartilage and bone on bone.
610
:Is that typically the main
one that you work with?
611
:dr--jeff-gross_2_05-01-2024_165332: That's
the most frequent it's that it's not,
612
:I mean, I'm not saying, Hey, you know,
that's what I, the only thing we'll do,
613
:we, we like to hear new problems to see
if we can find a solution or something
614
:to try, you know, um, you know, there
are new, you know, I didn't get to, say
615
:this earlier, you mentioned cancer, you
know, currently we're not using stem
616
:cells for cancer, but there are some new
newly identified types of exosomes that
617
:come from certain T cells in the immune
system that are known to kill cancer.
618
:We're looking at that very closely.
619
:Um, I'm not saying we can do it
yet, but, uh, I, I'm looking to
620
:incorporate that at some point.
621
:We're looking for these sort of more
specialized cell derived exosomes
622
:from different types of stem cells.
623
:Not just regular what we call
MSCs or mesenchymal stromal cells.
624
:Um, those are more for general
organ purposes or cartilage
625
:help, you know, joint help or
inflammation and across the board.
626
:But I like to see all kinds of patients.
627
:I like problems that no
one else can figure out.
628
:Uh, let's take a deep dive.
629
:We see a lot of patients all over the
country and outside the country by Zoom.
630
:And we, we, you know, help them
order whatever tests are needed.
631
:And only the patients we think
we can help do we invite to
632
:come see us here in Las Vegas.
633
:evan-_2_05-01-2024_165309: Yeah, I know.
634
:That's thank you for, for going
back and speaking about that.
635
:That's a major point.
636
:Uh, and a major topic to cover.
637
:Um, I know you also had mentioned
earlier, uh, zombie cells.
638
:Would you mind going a little deeper
on those, uh, for the listeners?
639
:dr--jeff-gross_2_05-01-2024_165332: Sure.
640
:You know, we have these cells in
our body and, and, and just like
641
:with our population of people,
you know, our very elder, older
642
:patients have trouble functioning.
643
:They have dementia, you know,
their heart function doesn't work.
644
:They have trouble getting around.
645
:They're, they're sort of the zombie cells.
646
:Um, they can't contribute, you know, like,
like they'd want to, or we want them to.
647
:So we have cells like that, that
are in our body, just kind of taking
648
:up space, using resources, using
nutrients, but not giving back.
649
:And those are called zombie cells, and
the more zombie cells you have, uh,
650
:the more diseases, the more problems,
the more The more aged that person is.
651
:So there's a lot of work in, in the
biochemical sciences, the molecular
652
:biology sciences to target those
cells and rid ourselves of them.
653
:There's a process of ridding ourselves
of cells, uh, called apoptosis.
654
:And we want to get rid of those cells.
655
:Things like the hot sauna, the other
hormesis type things, help us remove
656
:those zombie cells, recycle their parts.
657
:and renew, get that stem
cell activity going.
658
:We can also have zombie cells in
our stem cell population where
659
:they're not working as well either.
660
:So if you, if you're a smoker and you
drink too much and you've never exercised
661
:and you're obese and all kinds of
problems, you have a lot of zombie cells.
662
:evan-_2_05-01-2024_165309: Gotcha.
663
:Gotcha.
664
:And so I know with, um, with mitochondria,
it's, if I'm not mistaken, the younger,
665
:the mitochondria are the, like, the
more you have, obviously, like the
666
:better and more efficient they can be.
667
:And as you, um, you know, get stuck
in your ways, if you eat just like a
668
:really poor diet, they can get very
inefficient at, you know, burning
669
:multiple forms of energy and they
kind of get just stuck in their way.
670
:Uh, does the same thing kind
of happen with stem cells?
671
:Do they become inefficient as well?
672
:Essentially is that.
673
:Basically the same thing
that's happening there.
674
:dr--jeff-gross_2_05-01-2024_165332: Yeah.
675
:They're just like any cell in that way.
676
:They, they're, they're affected by what
they're exposed to, their activity.
677
:And what have you, and you're right
though, uh, mitochondria, the number
678
:of mitochondria in our cells and in our
muscle cells, particularly, uh, they're
679
:more than just a powerhouse of the cell.
680
:They, they help drive, you know,
uh, whether or not that cell
681
:is going to be a zombie or, or
divide or where we are with cells.
682
:There's a, there's also a set of
exosomes being looked at that are rich in
683
:mitochondria that can donate mitochondria.
684
:It's called mitochondrial,
uh, transfer therapy.
685
:And, um, it's being looked at first for
people who have actually mitochondrial
686
:diseases, but we're going to find
that it has use in the biohacking
687
:world, you know, to enhance your
maintenance of your muscle mass.
688
:And if, if you can maintain
your muscle mass, then you're
689
:maintaining your bones better.
690
:You maintain your stem
cell, you'll live longer.
691
:So that kind of thing.
692
:evan-_2_05-01-2024_165309:
That's, that's fascinating.
693
:That is super cool.
694
:Oh my
695
:dr--jeff-gross_2_05-01-2024_165332:
is all out there.
696
:It's happening.
697
:evan-_2_05-01-2024_165309: man.
698
:Okay.
699
:Yeah.
700
:So, uh, what, and is that one
of the things that you're kind
701
:of looking into currently?
702
:Cause I know you said, you're like,
you like to look into the things that
703
:people are not, you know, able to
figure out you like the hard challenge.
704
:Is that one of them,
705
:dr--jeff-gross_2_05-01-2024_165332: Yep.
706
:So we're, we're reaching forward.
707
:We're working with scientists to be one of
the places where you, you might be able to
708
:have access to these early, early things.
709
:Those aren't, you know, the, the cancer
killing ones and the mitochondrial
710
:rich ones aren't yet available,
but when you think about it, it
711
:might be a treatment for obesity.
712
:Inject these mitochondrial laden disease.
713
:Exosomes into fat, it converts white
fat to brown fat and brown fats, the
714
:stuff that goes away when you exercise.
715
:So, uh, we've got all kinds of great
ideas we're working on here and, uh,
716
:with in conjunction with good science.
717
:This is, we're not just
shooting in the dark.
718
:evan-_2_05-01-2024_165309: man,
that is no, that's exciting.
719
:I, I like that.
720
:Um, man, okay.
721
:We need to, we need to talk about
the stuff that's coming up and I
722
:want to be in touch with you on these
because, uh, it's very exciting stuff.
723
:And now I know we, uh, we're having a
little bit of a shorter episode today.
724
:Uh, just cause we had the
technical difficulties.
725
:So I'm going to probably want to bring
you back on, um, in the near future.
726
:If you're okay with that, dr.
727
:Jeff, and,
728
:dr--jeff-gross_2_05-01-2024_165332:
I would love it.
729
:Anytime.
730
:evan-_2_05-01-2024_165309: Yeah.
731
:And, but before we do go, I want
to, uh, give you an opportunity to
732
:kind of let people know how they
can get in touch with you, kind of
733
:what that process would look like.
734
:Um, of course I will share any
links that you would like in the
735
:description, uh, with our listeners,
but, uh, yeah, please let people know
736
:how to connect with you, how to find
you and, um, and reach out to you.
737
:Cause, um, Yeah, I feel like
everyone has the potential to
738
:gain some benefit from that.
739
:dr--jeff-gross_2_05-01-2024_165332:
Oh, thanks so much.
740
:Well, we, uh, our, our business name is
called re celebrate because you're, you're
741
:celebrating the renewal of yourselves.
742
:So it's R E.
743
:C E L L E B R A T E.
744
:So, uh, we're on, we're on the internet,
we're on Instagram, TikTok, Facebook,
745
:LinkedIn, where you just type in
ReCelebrate, you'll find us, message us
746
:through whatever, and go to our website
and fill out a little, uh, you know,
747
:reach out form and we'll get back to you.
748
:evan-_2_05-01-2024_165309: Amazing.
749
:Well, uh, you might be hearing
from me one of these days.
750
:My, uh, my dad might be one
of your future patients.
751
:I'm not going to lie.
752
:He's, uh, he's done, uh,
air conditioning for.
753
:Oh, probably almost 40 years now.
754
:I would say he's, uh, I think
he's turning 69 this year.
755
:So, um, yeah, he's, he's getting
up there and, um, that kind of work
756
:takes a toll on the body for sure.
757
:So you might be hearing from
me sooner rather than later.
758
:dr--jeff-gross_2_05-01-2024_165332:
We'd be happy to see them, of course.
759
:evan-_2_05-01-2024_165309: Amazing.
760
:Well, Dr.
761
:Jeff, thank you so much.
762
:I truly, truly appreciate you and, and
all of the work that you're doing as well.
763
:And pushing the needle in this
category is what it sounds like,
764
:which I really appreciate that you're.
765
:Uh, a trailblazer and helping many.
766
:So I appreciate that big time.
767
:dr--jeff-gross_2_05-01-2024_165332:
Thanks for having me on, Evan.
768
:It's awesome.
769
:evan-_2_05-01-2024_165309: Absolutely.
770
:All right, everyone.
771
:Well, thank you so much for joining us.
772
:You probably very likely going to have Dr.
773
:Jeff on another episode.
774
:So, uh, don't worry, we'll hear
more from him and, uh, thank
775
:you all very much for tuning in.
776
:Hope y'all have a great one and peace.